| |
Overall |
Madrid |
Andalusia |
MMR Concomitant |
| Incidence (CI95%) |
Incidence (CI95%) |
Incidence (CI95%) |
Incidence (CI95%) |
| Incidence of AEs by AC and co-vaccination with MMR |
| All AEs |
4.67 (4.27-5.10) |
4.75 (4.14-5.44) |
4.61 (4.11-5.17) |
4.73 (4.12-5.41) |
| ISR |
2.83 (2.57-3.11) |
2.69 (2.32-3.11) |
2.94 (2.59-3.31) |
2.68 (2.31-3.10) |
| Systemic Events |
1.31 (1.18-1.45) |
1.32 (1.12-1.54) |
1.31 (1.14-1.49) |
1.33 (1.13-1.56) |
| Solicited |
3.52 (3.21-3.85) |
3.78 (3.28-4.34) |
3.35 (2.97-3.77) |
3.76 (3.26-4.32) |
| Unsolicited |
0.78 (0.70-0.88) |
0.80 (0.67-0.95) |
0.77 (0.66-0.90) |
0.80 (0.67-0.96) |
| Incidence of SAEs by AC and co-vaccination MMR |
| All SAEs |
0.005 (0.002-0.013) |
0.009 (0.003-0.024) |
0.003 (0.001-0.011) |
0.009 (0.003-0.024) |
| ISR |
0.002 (0.000-0.007) |
0 |
0.003 (0.001-0.011) |
0 |
| Systemic Events |
0.004 (0.001-0.01) |
0.009 (0.003-0.024) |
0 |
0 |
| Solicited |
0 |
0 |
0 |
0 |
| Unsolicited |
0.005 (0.002-0.013) |
0.009 (0.003-0.024) |
0.003 (0.001-0.011) |
0.009 (0.003-0.024) |
| Incidence of ARs by AC and co-vaccination with MMR |
| SARs |
0.004 (0.001-0.010) |
0.004 (0.001-0.016) |
0.003 (0.001-0.011) |
0.004 (0.001-0.016) |
| ARs |
3.13 (2.85-3.43) |
3.30 (2.85-3.80) |
3.02 (2.67-3.40) |
3.28 (2.84-3.78) |
| ARs intensity |
| Mild |
1.70 (1.53-1.88) |
2.03 (1.74-2.36) |
1.50 (1.31-1.72) |
1.98 (1.69-2.31) |
| Moderate |
0.54 (0.47-0.62) |
0.44 (0.35-0.55) |
0.62 (0.52-0.73) |
0.45 (0.36-0.56) |
| Severe |
0.31 (0.26-0.37) |
0.29 (0.23-0.38) |
0.33 (0.26-0.40) |
0.30 (0.23-0.39) |
| ARs leading to a visit |
0.03 (0.02-0.04) |
0.01 (0.0-0.03) |
0.03 (0.02-0.06) |
0.03 (0.00-0.03) |
| ISR |
2.83 (2.57-3.11) |
2.69 (2.32-3.11) |
2.94 (2.59-3.31) |
2.68 (2.31-3.10) |
| Unsolicited |
0.16 (0.13-0.20) |
0.15 (0.11-0.21) |
0.17 (0.13-0.22) |
0.15 (0.10-0.21) |
| Solicited |
2.69 (2.44-2.95) |
2.69 (2.32-3.11) |
2.68 (2.37-3.03) |
2.68 (2.30-3.09) |
| Systemic Events |
0.32 (0.27-0.37) |
0.47 (0.38-0.59) |
0.22 (0.18-0.28) |
0.48 (0.38-0.59) |
| Unsolicited |
0.03 (0.02-0.05) |
0.04 (0.02-0.07) |
0.02 (0.01-0.04) |
0.04 (0.02-0.07) |
| Solicited |
0.30 (0.25-0.35) |
0.46 (0.36-0.57) |
0.20 (0.16-0.26) |
0.46 (0.36-0.57) |
| AEs Time of onset |
| Day0 |
18.39 (16.54-20.40) |
17.55 (14.83-20.65) |
18.98 (16.56-21.67) |
17.50 (14.77-20.60) |
| Day0-Day7 |
8.70 (7.91-9.54) |
8.99 (7.77-10.34) |
8.50 (7.51-9.58) |
8.95 (7.73-10.31) |
| Day8-Day30 |
0 |
0 |
0 |
0 |
|
