| 
      
        |  | Cluster Headache | Migraine Headache |  
        | Gender | Male 5:1 | Female 2:1 |  
        | Age of onset | Late 30s to early 40s | Menarche to early 20s, but    also in childhood |  
        | Family history | No | Yes |  
        | Aura | Never | May be present (20% of the time |  
        | Chronobiologic pattern | Yes | No |  
        | Onset-to-peak interval | Seconds to minutes | Minutes to 1 hr |  
        | Frequency | 2 or 3/day | Rarely >1/wk |  
        | Duration | 45 min | Usually <24 hr |  |