14 days

28 days

42 days

control

178.68±8.19

174.27±12.92

174.96±13.92

5 mg/kg group

176.98±10.35

169.85±13.06

172.41±12.29

15 mg/kg group

172.11±12.20

162.41±13.96*

166.40±8.80

30 mg/kg group

162.41±9.70**

153.98±9.99**

156.40±9.67**

45 mg/kg group

156.26±9.26**

149.84±9.26**

152.11±9.26**

60 mg/kg group

149.42±10.09**

144.14±9.56**

144.27±9.68**

Data are the means ± standard deviation (n=5×5)
*p<0.05, compared with the control group
**p<0.01, compared with the control group

Table 4: The average gray scales of Caspase-3 positive cells in the spleen