Compound

aLog D7.4

bClogP

[125I]-1, 1

3.60 ± 0.13

5.02

[125I]-2, 2

3.62 ± 0.14

5.02

o-BON

NR

4.29

m-BON

NR

4.59

SA4503

NR

3.47

aLog D7.4 values (means ± SD, n = 6) were determined by partitioning between n-octanol and phosphate buffered saline (pH 7.4). bClogP values were calculated using a fragment-based approach by a subroutine of program ChemBioDraw Ultra. NR = not reported
Table 1: Lipophilicity measures for SA4503 and radioiodinated analogs of SA4503.