Figure 2: Effects of MIF-1 and its analogue CF3-MIF-1 (both at a dose of 1 mg/kg, i.p.) on 1 hour restraint stress-induced analgesia (RSIA) estimated by PP test in male Wistar rats. Data are presented as mean ± S.E.M.; * P<0.05, *** P<0.001 vs. control; + P<0.05, ++ P<0.01 vs. MIF-1; xxx P<0.001 vs. RSIA.