Receptor Number of VS
hits
Number of VS
verified hits*
Hit Rate in % Number selective hits (Hit Rate^)
H3 19 13 68% 10 (76%)
H4 79 36 45% 2 (5%)
  74 33 (dual) 44% (dual) 17 (51%)
*Hits were defined as compounds with ≥ 50% inhibition at 20μM
^Percentage of the hits that were also selective or dual active compounds
Table 2: Statistics of VS results.