Compound
Molecular weight
QPlogPo/w
QPlogS
Human oral absorption
%Oral absorption
SSPC5
295.3
3.742
-3.793
3
85.43
SSPC8
263.2
2.460
-3.188
3
81.14
SSPC11
235.2
1.807
-2.333
3
69.57
SSPC14
311.2
2.885
-2.939
3
78.70
SSPC15
262.2
2.989
-2.436
2
71.38
Table 2:
Predicted ADME properties of the five best docked hybrid compounds.