compound Rotarod toxicity# % effect
30 min
Control 0/5 0
DMSO 1/5 25
IVa 5/5 100
VIb 5/5 100
IVc 5/5 100
VIc 4/5 80
IVd 5/5 100
clozapine 5/5 100
Table 3: Evaluation of neurotoxicity of test compounds and clozapine (3 mg/kg, i.p.) using rotarod test in mice.