S.No Entry R1 R2 R3 R4 R5 4Yield(%)a 1 4a (JBIR) H OMe OH H H 88 2 4b H OMe H H H 90 3 4c OMe H H H H 90 4 4d H H OMe H H 90 5 4e H OMe OMe H H 89 6 4f OMe OMe OMe H H 88 7 4g H OMe OMe OMe H 87 8 4h H OCH2O H H 86 9 4i Cl H H H H 85 aIsolated yields

Table 1: Synthesis of N1, N6-dihydrocinnamyl putrescine bisamides.