| |
n |
APA(mV) |
RP(mV) |
APD75(ms) |
APD90(ms) |
Vmax (V/s) |
|
Control |
8 |
117.4 ± 1.2 |
-80.9 ± 0.5 |
77.0 ± 2.2 |
94.1 ± 2.0 |
182.8 ± 2.5 |
| Quercetin |
|
|
|
|
|
|
|
0.1 mM |
8 |
117.6 ± 1.2 |
-80.6 ± 0.6 |
78.6 ± 2.4 |
95.0 ± 2.1 |
182.1 ± 1.2 |
|
0.3 mM |
8 |
117.8 ± 1.1 |
-80.7 ± 1.0 |
79.8 ± 3.8 |
97.3 ± 2.0 |
182.5 ± 2.3 |
|
1 mM |
8 |
114.6 ± 1.4 |
-80.4 ± 2.3 |
82.9 ± 2.3 |
100.3 ± 2.6 |
173.8 ± 2.21) |
|
3 mM |
8 |
113.7 ± 1.2 |
-79.7 ± 2.1 |
86.2 ± 2.01) |
110.9 ± 2.31) |
161.7 ± 2.42) |
|
Washout |
8 |
110.7 ± 1.0 |
-80.0 ± 0.6 |
79.4 ± 2.2 |
96.8 ± 2.4 |
172.3 ± 2.2 |
|
| Values are represented as mean ± S.E.M.
1)
: P<0.05,
2)
: P<0.01, with respect to
control value. |
| Table 1: Modulation of the action potential configurations by quercetin in guinea pig ventricular cardiomyocytes. |