Compd. R X Inhibition ratios for AChE (%)a Inhibition ratios forBChE (%)a
5a 0 7.88  ± 3.58 1.19  ± 0.59
5b 1 90.40  ± 1.23 26.05  ±  2.52
5c 1 37.02  ± 2.07 13.77  ± 1.05
5d 1 34.49  ±2. 76 9.02  ± 0.23
5e 2 19.28  ± 1.87 11.72  ± 0.82
5f 2 10.19  ± 0.44 9.52  ± 1.48
5g 2 16.54  ± 1.36 17.88  ± 2.83
5h 2 51.04  ± 0.55 39.20  ± 5.64
Rivastigmine - - 86.45  ± 0.71 94.60  ± 3.19
aInhibition ratios for AChE and BChE in the presence of 50 μM compound (means ± SEM of two experiments), AChE from electric eel, BChE from equine serum.
Table 1: Inhibitory activity of target compounds for AChE and BChE.