Compound Minimum inhibitory concentration (MIC) (μg mL-1)
     Antibacterial activity Antifungal activity
Gram +Ve bacteria Gram –Ve bacteria
S. aureus B. subtilis K. pneumonia E.coli C. albicans A. flavus
4a 100 50 >100 100 50 100
4b 25 12.5 25 50 3.12 6.25
4c 25 50 50 100 50 100
4d 100 50 25 50
4e 25 50           50 25 100 50
4f 12.5 25 100 12.5 50 >100
4g >100 50
4h 50 100 100 >100
4i 6.12 12.5 25 12.5 12.5 3.12
4j 25 25 50 25 6.25 12.5
Ciprofloxacin 12.5 12.5 25 12.5
Fluconazole 6.25 6.25
(─) No activity. Lower MIC values indicate higher the antimicrobial activity.
S. aureus: Staphylococcus aureus, B. subtilis:Bacillus subtilis, K. pneumonia: Klebsiella pneumonia, E.coli: Escherichia coli, C. albicans: Candida albicans.
Table 1: Antimicrobial activity (MIC profiles) of the synthesized compounds (4a–j).