Compound |
nOH |
NSR |
IC50(1)/IC50(i) |
ln[IC50(1)/IC50(i)] |
Ref. |
1 |
3.17 |
4.00 |
1.00 |
0.00 |
35 |
2 |
4.00 |
4.50 |
7.40 |
2.00 |
35 |
3 |
3.83 |
4.66 |
2.28 |
0.82 |
35 |
4 |
3.83 |
4.66 |
1.78 |
0.58 |
35 |
5 |
1.67 |
4.33 |
0.08 |
−2.53 |
35 |
6 |
3.00 |
5.00 |
0.20 |
−1.61 |
36 |
7 |
3.30 |
4.30 |
1.08; 0.75 * |
0.08; −0.29 |
36 |
8 |
3.00 |
6.00 |
0.14 |
−1.97 |
36 |
9 |
0.50 |
1.00 |
0.00; 0.00 * |
− |
36 |
10 |
2.83 |
4.50 |
0.09 |
−2.41 |
37 |
11 |
3.50 |
4.00 |
2.20; 1.80; 1.40 * |
0.79; 0.59; 0.34 |
37 |
12 |
2.50 |
3.00 |
0.016 |
−4.13 |
37 |
13 |
2.50 |
3.00 |
0.016 |
−4.13 |
37 |
|