Comp E.Coli K. pneumoniae S. aureus B. subtilis A. niger S. cerevisiae IIa 45 68 49 33 59 57 IIb 48 45 38 36 32 36 IIc 27 39 31 27 36 25 IId 52 62 74 37 61 51 IIe 67 69 49 45 52 77 IIf 58 68 77 43 31 27 IIg 24 38 30 25 56 57 IIh 76 88 82 67 72 72 IIi 60 70 55 62 61 46 IIj 22 36 28 23 29 23 IIk 63 69 58 41 90 58 IIl 51 88 79 52 47 68 IIm 36 51 47 34 60 48 Norfloxacin 15 29 24 16 -- -- Ketoconazole -- -- -- -- 21 13

Table 2: Minimum inhibitory concentration values (μg/ml) of derivatives (IIa-IIm) against microbes.