Positive Negative Total Positive 81 67 148 Negative 8 48 56 Total 89 115 204 ELISA (index test) Sensitivity ( 95 % CI) =91.0% (83.3 % - 95.4%) Specificity (95 % CI) =41.7% (33.1% - 50.9%) Likelihood ratio positive (95% CI) =1.6 (1.3-1.9) Likelihood ratio negative (95% CI) =0.2 (0.1-0.4)

Table 4: Performance of rESAT-6-CFP-10 antigen in the diagnosis of pulmonary TB in Ethiopia.