HLA Allele |
Controls n=524 |
LTI n= 218 |
PTB n=318 |
Controls vs LTI |
LTI vs PTB |
HLA-A* |
n (%) |
n (%) |
n (%) |
Pa |
OR |
95%CI |
P |
OR |
95%CI |
1 |
56 (10.69) |
20 (9.17) |
28 (8.81) |
|
|
|
|
|
|
2 |
132 (25.19) |
76 (34.86) |
82 (25.79) |
0.0098 |
0.63 |
0.45-0.89 |
0.0302 |
0.65 |
0.45-0.94 |
3 |
69 (13.17) |
16 (7.34) |
38 (11.95) |
|
|
|
|
|
|
11 |
43 (8.21) |
8 (3.67) |
26 (8.18) |
|
|
|
|
|
|
23 |
19 (3.62) |
5 (2.29) |
7 (2.20) |
|
|
|
|
|
|
24 |
40 (7.63) |
15 (6.88) |
35 (11.01) |
|
|
|
|
|
|
25 |
12 (2.29) |
6 (2.75) |
11 (3.46) |
|
|
|
|
|
|
26 |
16 (3.05) |
9 (4.13) |
8 (2.52) |
|
|
|
|
|
|
29 |
48 (9.16) |
22 10.09) |
30 (9.43) |
|
|
|
|
|
|
30 |
20 (3.82) |
9 (4.13) |
10 (3.14) |
|
|
|
|
|
|
31 |
13 (2.48) |
4 (1.83) |
9 (2.83) |
|
|
|
|
|
|
32 |
12 (2.29) |
9 (4.13) |
8 (2.52) |
|
|
|
|
|
|
33 |
16 (3.05) |
8 (3.67) |
14 (4.40) |
|
|
|
|
|
|
34 |
1 (0.19) |
0 (0.0) |
2 (0.63) |
|
|
|
|
|
|
66 |
4 (0.76) |
0 (0.0) |
0 (0.0) |
|
|
|
|
|
|
68 |
22 (4.20) |
9 (4.13) |
10 (3.14) |
|
|
|
|
|
|
74 |
0 (0.0) |
1 (0.46) |
0 (0.0) |
|
|
|
|
|
|
80 |
1 (0.19) |
1 (0.46) |
0 (0.0) |
|
|
|
|
|
|
aUncorrected p value. After Bonferroni correction for multiple comparisons p values were not significant.
The sum of the absolute numbers of the two alleles is twice the number of patients and controls. One PTB patient could not be HLA typed and for this reason in all the
tables n is 318 instead 320. |