Variablea Baseline (n=12) 3 months – baseline (n=12) 6 months – baseline (n=11)
Summary Pe Summary Pe
SGRQb          
Symptoms 52.4 (41.9, 79.2) -22 (-26.3, -9.3) 0.016 -6.5 (-27.6, -1.7) 0.12
Activity 62.8 (27.8, 70.8) 0.0 (-16.7, 11.6) 0.49 -0.9 (-19.6, 4.9) 0.43
Impacts 29.3 (20.7, 39.9) -2.5 (-4.8, 9.5) 0.79 -4.2 (-14.0, 9.3) 0.46
Total 42.2 (29.2, 55.3) -5.1 (-10.9, 6.5) 0.47 -7.4 (-16.2, 11.8) 0.37
SF-12c          
Physical subscale 38.3 (25.3, 50.3)d -1.7 (-7.6, 7.1) 0.58 2.3 (-4.1, 7.3) 0.63
Mental subscale 51.1 (41.2, 56.1)d 3.0 (-3.3, 10.8) 0.24 3.0 (1.0, 7.6) 0.049
aThe sample median (25th and 75th percentile) is given for numerical variables. bSt. George Respiratory Questionnaire (SGRQ) smaller index score indicates less chronic airflow limitations. cShort Form-12 (SF-12) scores have a mean of 50 and standard deviation of 10 in the general U.S. population; higher scores correspond to higher health levels. dSF-12 data was incomplete for one patient at baseline. eP-values refer to changes since baseline and result from Wilcoxon signed rank tests.
Table 4: St. George’s Respiratory Questionnaire & SF-12 Health Survey by visit.