Question TB Experts (n=29) Rheumatology Experts (n=12)
% Agreementb Median Range % Agreementb Median Range P Valuec
The TST is of diagnostic value for LTBI in patients with rheumatologic indications for TNFAB 86 4 2-5 92 4 2-5 0.30
IGRAs are good diagnostic tests for LTBI in patients with rheumatologic indications for TNFAB 83 4 2-5 83 4 2-5 0.76
The routine use of CXR is valuable in the assessment of rheumatology patients who are candidates for TNFAB, regardless of TST results 62 4 2-5 33 2 2-5 0.33d
CXR: Chest Radiographs; IGRAs: Interferon-Gamma Release Assays; LTBI: Latent TB Infection; TB: Tuberculosis; TNFAB: TNF-α blocking; TST: Tuberculin Skin Test
aLikert Response: 1, strongly disagree; 2, disagree; 3, neutral; 4, agree; 5, strongly agree ,bPercent of individuals within each group who select ”agree“ or ”strongly agree“, cComparison of distribution between groups by Wilcoxon one-way analysis of variance, dP=.057 by the Fisher exact test, excluding ”neutral“ responses
Table 1: Expert Opinion Regarding Assessment for LTBIa.