­ No. Sex F/M Age Months on Rx Dx Body temperature (°C) Hemoglobin (g/L) ESR (mm/h) Leukocytes  (x10°L) Smear  (+/-) Body weight (kg)
before after before after before after before after before after
V5 36 4/32   Mean 37.3±10.8 Median 34 Mean 3 Median3 Miliary=10 Cavitary=26 MDR=5 DR=4 TB/HIV=1 Mean 37.2±0.6 Median 38 117.7 ±16.4 119.4 ±15.4 22.7 ±15.4 13.3 ±9.9 7.9±3.1 6.2±2.4 36/0 11/25 57 ±10.7 59.2 ±10.9
P=0.21 P<0.0001 P=0.005 P<0.0001 P<0.0001

Control

36 7/29 Mean 42.9±11.8 Median 43.5 Mean 3.5±1.6 Median3.5 Miliary=14 Cavitary=22 MDR=6 DR=6 TB/HIV=2 Mean 37.4±0.5 Median 37 98.8 ±15.7 98.1 ±15.4 26.4 ±11.3 22.5 ±9.9 7.2±2.7 7.5±3.6 36/0 30/6 61.1 ±12.6 61.1 ±12.7
P=0.34 P<0.0001 P=0.49 P=0.02 P=1
Differences between two groups P=0.16 P=0.04 P=0.02 P=0.8 P=0.001 P<0.0001 P<0.0001 P=0.31 P<0.0001 P=0.87 P<0.0001 P=1.0 P<0.0001 P=0.14 P=0.46
Table 1: Summary of baseline data and treatment outcome in 72 treatment-failed TB patients treated with isoniazid and rifampicin alone (N=36) or in combination with V5 (N=36).