| Group |
Dose |
Traction test (%) |
| |
|
30 min |
60 min |
90 min |
| Control |
10 ml/kg |
0 ± 0.00 |
0 ± 0.00 |
0 ± 0.00 |
| Diazepam |
0.25 mg/kg |
100** ± 0.00 |
100** ± 0.00 |
100** ± 0.00 |
| n- Hexane |
50 |
3 ± 0.23 |
5 ± 0.59 |
12 ± 0.95 |
| 100 |
4 ± 0.45 |
9 ± 0.90 |
16 ± 0.95 |
| CHCl3 |
50 |
5 ± 0.06 |
8 ± 0.07 |
17.10 |
| 100 |
11 ± 0.95 |
20 ± 1.19 |
27.45 ± 1.10 |
| ETOAC |
50 |
0 ± 0.00 |
10 ± 0.75 |
15 ± 1.25 |
| 100 |
12 ± 0.89 |
23 ± 1.05 |
32.30 ± 2.15* |
| MeOH |
50 |
5 ± 0.3 |
11 ± 0.58 |
15 ± 1.75 |
| 100 |
13 ± 0.90 |
21 ± 1.54 |
29.22 ± 1.45* |
Values represent the percentages of mice (n=6) showing negative effects in the
traction test 30,60 and 90 min after treatment with distilled water (10 ml/kg), extract/
fractions 50 and 100 mg/kg) or diazepam (0.25 mg/kg). Data presented as mean ±
SEM (n=6) *P\0.05 and** P\0.01, both compared with controls. |
