Baseline preoperative 12 weeks postoperative The differences between baseline and 12 weeks postoperatively 52 weeks postoperative The differences between baseline and 52 weeks postoperatively
Variables          
(score) Mean(SD)/n Mean(SD)/n p-values Mean(SD)/n p-values
CMD-SQ:          
Anxiety1
(0-4)		 0.94 (1.2)/179 0.55(0.97)/156 p<0.001* 0.72(1.1)/116 p<0.001*
Concern1
(0-8)		 2.3 (2.3)/163 1.4(2.2)/151 p<0.001* 2.0(2.5)/109 p=0.15
Depression1
(0-6)		 0.7(1.4)/172 0.7(1.3)/156 p=0.52 0.7(1.3)/112 p=0.61
Somatoform Disorders1
(0-12)		 3.2(2.3)/148 3.3(2.7)/141 p=0.73 3.5(3.1)/98 p=0.60
Emotional Disorders1
(0-8)		 1.9(2.1)/170 0.5(0.9)/154 p<0.001* 1.5(2.2)/113 p=0.03*
Alcohol abuse1
(0-4)		 0.1(0.4)/166 0.1(0.4)/139 p=0.74 0.1(0.5)/104 p=0.98
Quality of Life1
(5-1)		 3.6(1.1)/198 3.7(1.0)/156 p=0.62 3.6(1.0)/116 p=0.78
OHS:          
Total score
(12-60)		 36.1(7.0)/174 24.4(8.7)/150 p<0.001* 19.8(8.8)/112 p<0.001*
EQ-5D-3L          
EQ-5DIndex
(-0.624 – 1)		 0.8(0.2)/169 0.9(0.1)/149 p<0.001* 0.9(0.1)/118 p<0.001*
EQ-5DVAS
(0-100)		 68.9(17.4)/142 76.3(15.9)/147 p<0.001* 76.0(19.8)/121 p<0.001*
Table 2: Summary of total sum scores at baseline; 12 and 52 weeks postoperative and the differences between them