Site Complication
Systemic Systemic infection
  Altered mental status
  Pain
External ear Otorrhea
Middle ear Temporal bone resorption
  Ossicular destruction
  Otic capsule destruction
  Tympanic membrane rupture
  Conductive hearing loss
Inner ear Sensorineural hearing loss
  Dysequilibrium due to vestibular dysfunction
Periauricular Local infection
  Mastoid infiltration (e.g. acute mastoiditis)
  Facial nerve paresis/transsection
  Cutaneous fistulas
  Cervical abscess (Bezold's abscess)
  Postauricular pain
  Postauricular swelling
Intracranial Invasion of posterior fossa
  Temporal lobe abscess
  Parietal lobe abscess
  Cerebellar abscess
  Extradural abscess
  Invasion of the labyrinth and Fallopian canal
  Lateral sinus thrombosis/thrombophlebitis
  Subdural abscess
  Meningitis
Table 1: Complications of middle ear cholesteatoma.