Moxifloxacin- Limit of detection (LOD) & Limit of Quantification (LOQ) |
S.No. |
Injection No. |
Slope |
Y-Intercept |
R2 |
1 |
Inj-1 |
23059.4 |
27156.504 |
0.999 |
2 |
Inj-2 |
23184.9 |
25399.4381 |
0.999 |
3 |
Inj-3 |
23070.2 |
31121.98583 |
0.998 |
Average |
23104.8333 |
27892.6426 |
0.9987 |
STDEV |
69.550 |
2931.435 |
0.001 |
LOD=3.3 x σ/S |
LOD |
0.4 |
ppm |
|
|
LOQ=10 x σ/S |
σ = Standard deviation of y-intercepts of regression line |
S= slope of the linearity curve |
LOQ |
1.3 |
ppm |
|
|
Acceptance Criteria: LOD & LOQ values shall be less than the minimum linearity concentration |