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Cold atmospheric plasma (CAP) is increasingly used in medical applications for eradication of bacterial and tumor cells. CAP treatment devices, known as plasma jet pens, produce reactive oxygen and nitrogen species at atmospheric pressure and room temperature. The produced reactive species are concentrated in a small and pre.. Read More
Parvovirus 4 (PARV4) is one of the emerging human parvoviruses discovered recently. PARV4 has long-lasting persistence in tissues after primary infection, but persistent PARV4 viremia has yet to be effectively detected in humans. In the present work, longitudinal serum samples from eleven patients with antiphospholipid syndr.. Read More
Dyspepsia is a common symptom of gastrointestinal disease with global distribution. The prevalence of this disorder varies between 3% and 40%. Dyspeptic symptoms account 10% of hospital admissions in Ethiopia. The aim of this study was to determine the contributing factors for dyspepsia at Yirga cheffe primary hospital, Sout.. Read More
Chagas disease is one of the most important zoonosis affecting the Latin America. Despite important progress
achieved in last decades through strategies at regional level against vectoral transmission and improvement of
screening among blood donors, the disease continues to represent a public health priority. Knowledge on
.. Read More
Background: Development of drug resistance in bacteria is a common and alarming problem worldwide and there is continuous and urgent need of antibacterial agents. Endophytes offer a plethora of secondary metabolites with various biological activities. These secondary metabolites may help the host plant in defense from pathogens .. Read More
Purpose: To develop a multiplex-urease PCR assay specific for ureA and ureB genes directly from gastric biopsy specimens and compare the results of multiplex-urease PCR assay with rapid urease test (RUT) and histopathology.
Methodology: This study was conducted on 109 patients. A RUT was run; histopathological staining and mult.. Read More
Objective: The objective of this study was to determine the bacterial etiology of diarrhoeal disease in children and the antibiogram of the isolates.
Methods: The study was carried out in Bharatpur Hospital, Chitwan, Nepal form May 2014 to Oct 2014. Stool specimens were collected from children at paedriatic ward aseptically and.. Read More
Background: In developing countries diarrheal diseases in children are a major public health concern.
Objectives: This study investigated the incidence and antibiotic susceptibility profile of Escherichia coli and Salmonella causing Childhood Diarrhea in Awka.
Methods: Twenty six (26) diarrheic stool samples were collected fro.. Read More
Histoplasmosis is an important systemic fungal infection in endemic areas. It has been reported from various states of India, with particular endemicity in north-eastern regions. Most infections are asymptomatic or self-limited, some individuals develop acute pulmonary infections or severe and progressive disseminated infect.. Read More
DNA replication has been extensively studied in a number of bacterial species, which possess a unipartite genome consisting of a single circular chromosome. Approximately 10% of sequenced bacterial species have a multipartite genome structure, which is comprised of multiple chromosomes. However, the coordination and regulation o.. Read More
Pseudomonas aeruginosa is an important opportunistic pathogen in human infections. P. aeruginosa is naturally resistant to many antibiotics and mutations can result in resistance development during treatment as well. Piperacillin/tazobactam and Ticarcillin/clavulanate are β-lactam/β-lactamase inhibitor combination with.. Read More
Enterococci often acquire antimicrobial resistance through horizontal gene transfer. Relatedness between enterococci with high level resistance to gentamicin and vancomycin isolated from humans, food and hospital environment in Tandil County (Argentina) was investigated. PCR amplification for species determination was carried ou.. Read More
Introduction: ALCAM as a glycoprotein is a member of the immunoglobulin family and plays an important role in cell growth, survival and motility. This protein also contributes to the development of tumour invasion in colorectal and breast cancers and is typically considered as a cancer stem cell marker. ALCAM as a cell-surface a.. Read More
Introduction: This study was carried out using a multistage cross sectional study to evaluate the extent of knowledge on HIV/AIDS and its effects on youths in the North West Region of Cameroon. Method: The study was carried out on 1,120 (690 females and 430 males) students aged 15-24 years who consented to participate in the stu.. Read More
P. aeruginosa may be involved in the poisoning of food. It is highly pathogenic to immunocompromised subjects or weakened, causing a high rate of morbidity and mortality. The aim of this study was to determine the phylogenetic marker suitable for molecular identification of Pseudomonas aeruginosa. The purity and concentratio.. Read More
Most multidrug resistant (MDR) Escherichia coli isolates (resistant to more than 3 classes of antibiotics) exhibit co-virulent characteristics that contribute to mortality and morbidity as a result of resistance to commonly prescribed antibiotics in the clinics. This study evaluated phenotypically some virulent characteristi.. Read More
Multidrug resistant (MDR) E. coli associated infections remains one of the most important bacterial infections that have contributed significantly to increased morbidity and mortality in clinical settings. One of the known resistant mechanisms of MDR bacteria is reduced cell wall permeability, which is controlled by outer me.. Read More
Background: Carbapenem-resistant Gram-negative rods (CR-GNR) are gaining increasing importance in healthcare settings, especially in high-dependency units and among critically ill patients. These bacteria are frequently resistant to all antibiotics except colistin, some aminoglycosides and variably tigecycline, posing a seri.. Read More
Background: Buschke-Löwenstein tumor (BLT) or giant condyloma acuminatum (GCA), is a rare disease caused by Human Papilloma virus (HPV) types 6 and 11, more common in immunocompromised males. We describe a rare case of BLT associated with mixed low and high-risk HPV type’s infection in a very young immunocompetent fem.. Read More
Pseudomonas aeruginosa is one of the most common causes of nosocomial infections. Hospital associated infection by multidrug resistant (MDR) strains constitute a serious problem worldwide. The aim of the present study was to evaluate whether exposure to sub-MIC levels of anti-pseudomonas antibiotics and reactive oxygen species.. Read More