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Acute Haemorrhagic Leucoencephalitis (AHLE) is a rare disorder which was first described by Weston Hurst in 1941. It has been acknowledged as severe form of acute disseminated encephalomyelitis, characterized by acute onset and rapid progression of inflammation of the brain with associated necrosis and haemorrhage. We report an .. Read More
Late Infantile Neuronal Ceroid Lipofuscinoses is an inherited neurodegenerative condition caused by a mutation in the CLN2 gene that codes for an enzyme, tripeptidyl peptidase I (TPP-1). Deficiencies in TPP-1 lead to protein accumulation within lysosomes and subsequent neuronal death, which produce the clinical features of the d.. Read More
Coronary heart disease (CHD) is one of the main causes for mortality and morbidity in both develop and developing countries throughout the world. CHD had claimed nearly 7.4 million deaths worldwide according to WHO in 2015.
Wellens’ syndrome is now being increasingly recognized as a distinct entity causing acute coronary .. Read More
Background: Discussion has been continued concerning Calorie Restriction (CR) and Low Carbohydrate Diet (LCD). For years, authors have investigated LCD associated with lipids, renal function and Ketone Bodies (KB) for clinical application of super LCD formular meal. In this study, 3-hydroxybutyric acid (3-OHBA) and acetoacetic a.. Read More
Angioedema is a condition described as a transient, non-pruritic, non-pitting and self-limiting local swelling of cutaneous and mucosal tissues that completely resolve in 1 to 5 days. Acquired C1-inhibitor deficiency or acquired angioedema (AAE) may be associated with a lymph proliferative disease. We report the case of a 52 yea.. Read More
The article summarizes the clinical study, which showed that in non-alcoholic steatohepatitis that develops on the background of obesity and chronic kidney disease I-III stage, the presence of fibrotic changes in the liver tissue was found, which according to the biochemical index of fibrosis, exceeds those in patients with non-.. Read More
Lung adenocarcinomas in metastatic phase are unfortunately still burdened with a short period of survival. In this paper I present the case of Mr. SC, 70 years old, which came to my observation with widespread pre-treated disease. A personalized combination of chemotherapy and hyperthermia has made it possible to prolong surviva.. Read More
Background: Over recent decades, more pregnant women around the world have undergone labor induction to deliver their babies. In developing countries up to 25% of all deliveries at term now involve induction of labor, but in some developing countries the rate are generally lower. Induction is indicated when the benefits to eithe.. Read More
The aim of this study was to investigate the probable immune mechanisms of PI-IBS.
C57L/B6 mice, which have been infected by 500 Trichinella larvae for 56 days, were used to PI-IBS model mice, the levels of the intestinal mRNAs and proteins of c-kit, interleukin-10 (IL-10), and IL-17 were measured by RTPCR and.. Read More
Ten patients suffering from pathology considered to be refractory ME/CFS have been prospectively offered treatment with a novel nutriceutical that increases the activity of pyruvate dehydrogenase and enhances mitochondrial energy production by the aerobic metabolism of the Kreb’s cycle. Whereas half of the patients present.. Read More
A 72-years-old woman was admitted for severe Acute respiratory distress syndrome (ARDS) with acute renal failure and proteinuria. Anti-glomerular basement membrane (ABMA) disease was confirmed with anti-GBM antibodies and renal biopsy but no lung hemorrhage was found. To our knowledge, the association between ARDS and ABMA disea.. Read More
Background: Primary biliary cirrhosis (PBC) is an autoimmune disease. Implication of TNF alpha in its pathogenesis has been suggested.
Findings: We describe the case of a 56-year-old female patient with rheumatoid arthritis (RA) treated with anti- TNF alpha agents (Infliximab). During this treatment, perturbation of liver tests.. Read More
Objectives: The expansion of competency based medical education (CBME) has necessitated the development of novel assessment tools. Social media applications hold potential to become entrenched E-learning assessment tools. The objective of this study was to evaluate WhatsApp as an assessment tool to improve trainees’ confid.. Read More
Aim: The aim of the current study was to assess the correlation between the Ulcerative Colitis Endoscopic Index of Severity (UCEIS), Lichtiger Index and the fecal calprotectin (FC) levels in ulcerative colitis (UC) patients.
Methods: This prospective study included 58 patients with UC, referred for colonoscopy to our Center. Th.. Read More
A 60-year-old male, with past medical history significant for traumatic total splenectomy in 1970, osteoarthritis, presented with symptoms of fever, chills, fatigue, and bilateral knee pain and swelling of several days duration. Physical examination was significant for bilateral knee effusion, redness, warmth, and decreased rang.. Read More
Introduction: Patients who survived Acute Respiratory Distress Syndrome (ARDS) may present long term physical damage that affects their quality of life and respiratory capacity. Restrictive ventilatory disorders, decrease in pulmonary diffusing capacity and changes in quality of life were observed.
Objective: Know whether there.. Read More
Background: Ablation therapy with advances in its techniques becomes widely used in patients with hepatocellular carcinoma. Ablative techniques can induce tumor cell death and stimulate many immunological responses. These responses can be evaluated through assessment of peripheral immune cells changes in systemic circulation. Ai.. Read More
Buruli ulcer is a neglected skin disease caused by Mycobacterium ulcerans (MU), and affects 1000 people each year worldwide and particularly in African countries. Eradication of Buruli ulcer is difficult because of the lack of early diagnostic in rural endemic regions, and the unknown of the disease in national health care syste.. Read More
Diabetes mellitus is a metabolic disorder of multiple aetiology. Destruction of pancreatic beta cells, hyperglycaemia, and insulin deficiency cause type 1 diabetes mellitus. Diabetic nephropathy is the damage to kidneys because of diabetes. It is predominantly seen in patients with type 1 diabetes (insulin-dependent type) and ty.. Read More
Male infertility is the inability of a male partner to achieve a pregnancy in a fertile female partner. The purpose of this paper is to determine of infertility in infertile men in the Dukagjini Region of Republic of Kosovo. Materials and Methods, Measurement of hormonal parameters is made with the apparatus Biomerieux Mini Vida.. Read More