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Microbial Organisms in Tissue Culture
Bacterial and fungal pollutants generate a main problem in plant tissue culture research laboratory. This study meant at exploring the sources of microbial contamination in tissue culture laboratory. The bacterial pollutants comprise Pseudomonas fluorescents’, Escherichia coli, Proteus sp, Micrococcus sp, Streptococcus pne.. Read More
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Low Back Pain Treatment Without Using Any Anti-Inflammatory Medications & Surgery
Lower back pain can have causes that aren't due to underlying disease. Examples include overdoing such as working out or lifting too much, prolonged sitting and sleeping in an uncomfortable position, laying down, wearing a poorly suitable backpack. If someone deal with back pain, it can make feel dejected. Whether it’.. Read More
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Highlights & Achievements of Biochemistry and Physiology: Open Access Journal
Dear Readers The Journal covers a wide range of biological processes at biochemical and molecular level in all living organisms including humans, animals, plants and microbes. This reputed Biochemistry and Physiology journal publishes articles related to clinical chemistry, molecular biology and genetics, therapeutic drug monito.. Read More
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As per current definition recognized by Food and Agricultural Organization of the United Nations (FAO) and world health organization (WHO) working group experts is that probiotics are live strains of strictly selected microorganisms, which once administered in adequate amounts, give a health benefit to the host. Globally non-alc.. Read More
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Association of Vitamin D Status with Pulmonary Function in Adult Asthmatics: A Case Control Study
Calcitriol is the active form of Vitamin D. 7-Dehydrocholesterol in our skin gets converted to cholecalciferol when it is exposed to sunlight which gets hydroxylated in liver and kidney to finally form 1,25-DihydroxyCholecalciferol (Calcitriol) which is the active form of Vitamin D. The role of calcitriol in physiological and pa.. Read More
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Oxidative stress is one of the significant factors in the pathogenesis of several retinal diseases, viz. age-related macular degeneration, diabetic retinopathy, etc. Available treatments are not fully effective in attenuating tissue damage and the associated vision loss. Hence development of newer therapeutic compounds is highly.. Read More
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Diagnostic Value of CD49d Expression in Patients with Chronic Lymphocytic Leukemia
This study was carried out on 41 newly diagnosed chronic lymphocytic leukemia (CLL) patients for investigation of the diagnostic value of CD49d and its correlation with disease outcome in CLL patients. CD49d expression on CLL cells in peripheral blood samples was estimated by flow cytometry analysis. Patients with ≥ 31.5% .. Read More
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U-74389G Significantly Reduced TNF-α in a Swine Model of Acute Liver Ischemia-Reperfusion Injury
Introduction: Ischemia-reperfusion injury (IRI) is one of the main causes of increased morbidity in hepatic surgery following portal triad clamping and blood reflow.Aim: The aim of this study was to determine whether intraoperative administration of the lazaroid U-74389G can reduce inflammatory activity in landrace pigs undergoi.. Read More
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The pyrimidine biosynthetic enzyme Cytidine 5’-triphosphate (CTP) synthetase has an important role in the biosynthesis of RNA, DNA and phospholipids. The synthetase has been found to be highly regulated at the level of enzyme activity and enzyme synthesis in both prokaryotes and eukaryotes including humans. The enzyme has .. Read More
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Background: Soy contains phytoestrogens which are potent endocrine disruptors. Soy mainly contains phytoestrogens called isoflavones predominantly daizein and genistein. Main body: The present study determined the effects of isoflavones consumed post-weaning on prepubertal and postpubertal Leydig and Sertoli cell numbers, sperma.. Read More
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Role of Advanced Glycation End Products (AGE) in Health and Disease: An Overview
Advanced Glycation End products (AGEs) are products derived from the reaction between reducing sugars and the aminoacids. The process of covalent linkage of a sugar with a protein or an amino acid is called as glycation. The AGEs are formed exogenously from animal derived foods which are rich in fat and protein. AGEs can be endo.. Read More
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Background of study: Annona muricata; commonly known as sour sop has been reported to possess ethno medicinal values including anti-tumor and antioxidant activity.Aim: This research was aimed at evaluating the phytochemical composition and the phytoestrogenic, hypocholesterolemic and antioxidant activity of Annona muricata seed .. Read More
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Physiological and ultrastructural investigations have been carried out on Procambarus clarkii exposed to sublethal concentrations of Spinosad insecticide. The study showed that the highest mortality percentage was 88% for males and 70% for female occurred at 64 × 10³ ppm Spinosad. The lethal toxicity (LC50) was 24.1 g/.. Read More
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Endurance exercise (EXE) is a potent inducer of both muscle fiber transformation as well as autophagy in skeletal muscles. However, it has remained unknown whether autophagy is associated with EXE-induced muscle fiber transformation. Thus, we examined autophagy responses in in fast muscle (tibialis anterior; TA) tissues after si.. Read More
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Preventing Carcinogenesis with Compounds that Inhibit Cytochrome P450 1A1 and 1B1
Cytochrome P450 1A1 and 1B1 convert polycyclic aromatic hydrocarbons to carcinogenic compounds in extrahepatic tissues. In 1997, resveratrol, a naturally occurring stilbene found in grapes and red wine, was found to inhibit the growth of tumors and that one potential mechanism was by inhibiting cytochrome P450 1A1 and 1B1. This .. Read More
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Diabetes mellitus is a metabolic disease assuming hyperglycemia as its main symptom, and the number of patients has continued increasing all over the world. Its major complications such as neuropathy, nephropathy and retinopathy by microangiopathy and cerebral vascular disease and heart disease by macroangiopathy, are well known.. Read More
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The pyrimidine salvage enzyme cytosine deaminase occupies an important function in the effectiveness of substrate mediated enzyme prodrug chemotherapy. The basis of this chemotherapeutic approach is that cytosine deaminase can catalyze the deamination of 5-fluorocytosine to 5-fluorouracil.The resultant 5-fluorouracil formed is a.. Read More
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Comparison of Extremely Halophilic Archaea Isolated from Three Salt Lakes in China
There’re many kinds of extremely halophilic archaea living in salt lakes all over the world and the ecological environment of lakes can affect their archaeal species. To illustrate the relationships between archaeal species and salt lake environment, we isolated and cultured 25 extremely halophilic archaeal strains from th.. Read More
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Soy Isoflavones (from Glycine max) in Menopause Health and Diseases
As per the third consensus meeting of Indian Menopause Society reports, the number of postmenopausal women in India is approximately 43 million and it is projected to be 103 million by 2026. While the average age for menopause in India is 47.5 years, there is an alarming increase of premature menopause among the Indian women has.. Read More
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Targeting Demalication and Deacetification Methods: The Role of Carboxylic Acids Transporters
As weak organic acids, carboxylic acids partially dissociate in aqueous systems, like wine, establishing equilibrium between uncharged molecules (undissociated form) and their anionic form, according to the medium pH and their pKa. This property influences yeasts cell-behaviour, particularly the mechanisms by which the molecules.. Read More
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