One of the positive symptoms of schizophrenia is auditory hallucination. Studies suggest that frontal and temporal lobes are involved in this disturbance. Another research demonstrates that in schizophrenic patient the level of NMDA (N-methyl-D-aspartate) receptor subunits such as NR2D increases in the prefrontal cortex, which may lead to abnormal receptor activation which can cause irregular situations such as delusions and hallucinations. reactivation of NMDA receptors by SRR in temporal lobe of schizophrenic patients may be one of the involving factors which produced auditory hallucinations. Surely experimental studies are needed to validate this hypothesis.
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Last date updated on November, 2020