Epidemiological studies and clinical trials indicate conclusively that high serum cholesterol is a major risk factor for coronary heart disease and that lowering cholesterol levels reduces the risk .The three major sizes of lipoprotein particles in which cholesterol circulates in the plasma are: very low density lipoprotein cholesterol (VLDL-C) low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C). Several large epidemiological studies suggest that for each 1 mg.dLâ1 increase in HDL-C, there is an accompanying 2% decrease in coronary heart disease risk in men and a 3% decrease in women. A low LDL-C level does not eliminate the risk impacted by a low HDL-C but a high HDL-C appears to offset some of the risk of a high LDL-C. HDL-C is the âgarbage trucksâ of the blood system, collecting cholesterol and dumping it into the liver. HDL-C plays a critical role in reverse cholesterol transport. It may retard atherogenesis by maintaining endothelial function
Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity. The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on September, 2014