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A form of cell death in which a programmed sequence of events leads to the elimination of cells without releasing harmful substances into the surrounding area. Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unnecessary cells, and unhealthy cells. The human body replaces perhaps one million cells per second. Apoptosis can play a role in many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal, for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's diseases also known as cell
suicide or programmed cell death or apoptosis.
The Impact Factor, often abbreviated IF, is a measure reflecting the average number of citations to recent articles published in science and social science journals. IF is calculated by dividing the number of citations in the Journal Citation Reports year by the total number of articles published in the two previous years. High impact factor for a particular journal implies good number of citations and quality of work. Because of the open access journals, impact factors are improving. Open access journal articles are essentially peer-reviewed and available for access through the directory of Open Access journals. Each open access journal delivers the latest updates in the respected research area in various formats so that subscribers can access the same through various options.