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Castleman Disease

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  • Castleman disease

    Definition:
    Castleman disease is a rare disorder that involves an overgrowth (proliferation) of cells in your body's disease-fighting network (lymphatic system). Also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia, Castleman disease can occur in a localized (unicentric) or widespread (multicentric) form.

  • Castleman disease

    Fever. Night sweats. Fatigue and weakness. Loss of appetite. Unintended weight loss. Enlarged lymph nodes, usually around the neck, collarbone, underarm and groin areas. Enlarged liver or spleen.
  • Castleman disease

    Statistics:
    From July 2004 through January 2005, to look for the virus in blood and saliva, we conducted the study reported here, an HHV-8 survey at the same blood bank. A total of 577 volunteer blood donors (431 men and 146 women), mean age 39 years (range 17–76 years), were enrolled at the Hemotherapy Service, Hospital of Infectious Diseases “Francisco Javier Muñiz.” The protocol was approved by the Teaching and Research Committee.

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