Female infertility refers to infertility in female humans. It affects an estimated 48 million women treatment : Clomiphene citrat: Clomiphene citrate (Clomid, Serophene) is taken by mouth and stimulates ovulation by causing the pituitary gland to release more FSH and LH Gonadotropins: Instead of stimulating the pituitary gland to release more hormones, these injected treatments stimulate the ovary directly Metformin. Metformin (Glucophage, others) is used when insulin resistance is a known or suspected cause of infertility, usually in women with a diagnosis of PCOS. Letrozole. Letrozole (Femara) belongs to a class of drugs known as aromatase inhibitors and works in a similar fashion to clomiphene Bromocriptine. Bromocriptine (Parlodel, Cycloset) may be used when ovulation problems are caused by excess production of prolactin (hyperprolactinemia) by the pituitary gland. Laparoscopic or hysteroscopic surgery,Tubal ligation reversal surgery (microscopic),Tubal surgeries,Intrauterine insemination (IUI),Assisted reproductive technology.