alexa Lynch syndrome | Argentina| PDF | PPT| Case Reports | Symptoms | Treatment

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Lynch Syndrome

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  • Lynch syndrome

    Pathophysiology
    Lynch syndrome is the familial clustering of colorectal and endometrial cancers. This syndrome is passed in an autosomal dominant fashion within families with defective mismatch repair as the genetic basis for cancer development in these patients.

  • Lynch syndrome

    Statistics
    Argentine families presented a high incidence of stomach cancer. The elevated incidence of breast cancer and its association with a novel hMSH2 mutation bring to consideration the inclusion of this malignancy as part of the syndrome. A lack of awareness by both physicians and persons at risk was observed.

  • Lynch syndrome

    Treatment
    Surgery for Lynch syndrome colon cancer is more likely to involve the removal of more of the colon, since people with Lynch syndrome have a high risk of developing additional colon cancer in the future.

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