Neuroblastoma is a cancer that develops from immature nerve cells found in several areas of the body. Neuroblastoma most commonly arises in and around the adrenal glands, which have similar origins to nerve cells and sit atop the kidneys. However, neuroblastoma can also develop in other areas of the abdomen and in the chest, neck and near the spine, where groups of nerve cells exist. Signs and symptoms of neuroblastoma vary depending on what part of the body is affected.
Neuroblastoma in the abdomen the most common form may cause signs and symptoms such as: 1. Abdominal pain 2. A mass under the skin that isn't tender when touched 3. Changes in bowel habits, such as diarrhea 4. Swelling in the legs. Other signs and symptoms that may indicate neuroblastoma include: 6. Lumps of tissue under the skin 7. Eyeballs that seem to protrude from the sockets (proptosis) 8. Dark circles, similar to bruises, around the eyes 9. Back pain 10. Fever 11. Unexplained weight loss 12. Bone pain