Lymphoma is cancer that begins in cells of the lymph system. The lymph system is part of the immune system, which helps the body fight infection and disease. Because lymph tissue is found all through the body, lymphoma can begin almost anywhere. Non-Hodgkin's lymphoma is cancer that originates in your lymphatic system, the disease-fighting network spread throughout your body. In non-Hodgkin's lymphoma, tumors develop from lymphocytes. Non-Hodgkin's lymphoma is more common than Hodgkin lymphoma. Of the 927 cases, 809 (87.3%) were B-cell lymphomas and 118 (12.7%) were T-cell lymphomas. Overall, the distribution of B- and T-cell NHL was similar in CSA (87.3% vs 12.7%) and NA (90.4% vs 9.6%; P = .1). However, among mature B-cell NHL, the frequency of high-grade lymphomas was significantly greater in CSA (52.9%) compared with NA (37.5%; P < .0001;)
When non Hodgkin lymphoma is diagnosed a team of doctors and other professionals work together to decide on the best treatment for each person. The main types of treatment for NHL are chemotherapy, radiotherapy, and biological therapy. Scientists are making a lot of progress in understanding how changes in DNA can cause normal lymphocytes to develop into lymphoma cells. Once this is understood, drugs may be developed that block this process.