Nonulcer stomach pain is a term used to describe signs and symptoms of indigestion that have no obvious cause. Nonulcer stomach pain is also called functional dyspepsia or nonulcer dyspepsia. The overall prevalence of dysphagia was 12.9% (95% CI, 10.6?15.2) and for frequent dysphagia, the rate was 3.5% (95% CI, 2.2?4.7). Dysphagia was significantly higher among females (17.1%) than among males (8.4%) (P < 0.05). All affected subjects reported having the symptom for 5 years or more, and 6.7% reported that the symptom was severe or very severe. Among those reporting dysphagia, 27.9% also experienced odinophagia, 57.3% reported dysphagia to solids only, 8.7% to liquids only and 34.0% to both.
Treatment with medications has variable success. Some patients obtain relief from antacids or acid-suppressing drugs, and some patients with symptoms suggestive of a problem with stomach emptying may be helped by medications which increase emptying. Antacids and sucralfate were found to be no better than placebo in a literature review. H2-RAs have been shown to have marked benefit in poor quality trials (30% relative risk reduction), but only a marginal benefit in good quality trials.