Primary lateral sclerosis (PLS) causes weakness in your voluntary muscles, such as those you use to control your legs, arms and tongue. Primary lateral sclerosis is a type of motor neuron disease that causes muscle nerve cells to slowly break down, causing weakness.Primary lateral sclerosis can happen at any age, but it usually occurs between ages 40 and 60.
Further assuming an average disease duration of 20 years (close to the reported median of 19 y), this prevalence would translate into an annual PLS incidence rate of 1 per 10 million (0.01 case per 100,000 population per year), which is approximately 0.5% of that for ALS. They are consistent with a conservative estimate that not more than 500 people with PLS currently are living.
Physical therapy, Stretching and strengthening exercises may help to maintain muscle strength, flexibility and range of motion, and to prevent joint immobility. Heating pads can help relieve your symptoms of muscle pain. The treatments for primary lateral sclerosis (PLS) focus on relieving symptoms and preserving function. There are no treatments to prevent, stop or reverse PLS.