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Pathophysiology
Prion disease represents a group of conditions that affect the nervous system in humans and animals. In people, these conditions impair brain function, causing changes in memory, personality, and behavior; a decline in intellectual function (dementia); and abnormal movements, particularly difficulty with coordinating movements (ataxia). The signs and symptoms of prion disease typically begin in adulthood and worsen with time, leading to death within a few months to several years.
Statistics
This study describes the occurrence and epidemiology of CJD and vCJD . The following attempts to extrapolate the above incidence rate for Prion disease to the populations of 15,823,9572, total 17 extrapolated incidences are recorded in Argentina.
Treatment
A number of potentially useful drugs have been used in experimental animal prion diseases or in patients in an attempt to alter the course of the disease. Quinacrine: The antimalarial compound, Pentosan polysulphate (PPS): PPS is a semi-synthetic chemical derived from shavings of beech wood, Tetracyclic Compounds, Flupirtine are commonly used drugs.