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Septic Arthritis

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  • Septic Arthritis

    Septic Arthritis is also known as infectious arthritis, bacterial, or fungal arthritis. It is the purulent invasion of a joint by an infectious agent which produces arthritis. The condition is an inflammation of a joint that's caused by infection. Typically, septic arthritis affects one large joint in the body, such as the knee or hip. Less frequently, septic arthritis can affect multiple joints. Septic arthritis is considered a medical emergency. If untreated, it may destroy the joint in a period of days. The infection may also spread to other parts of the body.

  • Septic Arthritis

    Pathophysiology: The major consequence of bacterial invasion is damage to articular cartilage. This may be due to the particular organism's pathologic properties, such as the chondrocyte proteases of S aureus, as well as to the host's polymorphonuclear leukocytes response. The cells stimulate synthesis of cytokines and other inflammatory products, resulting in the hydrolysis of essential collagen and proteoglycans. Infection with N gonorrhoeae induces a relatively mild influx of white blood cells (WBCs) into the joint, explaining, in part, the minimal joint destruction observed with infection with this organism relative to destruction associated with S aureus infection.

  • Septic Arthritis

    A total of 30 patients with 35septic joints were studied. Eighteen (60%) were males and 12(40%) were female with a male to female ratio of 1.5:1. Age range was 3months and 75years. The knee was the commonest 16(45.7 %) joint involved followed by the hip joint 11(31.4%). Staphylococcus aureus was the commonest organism cultured in joint aspirate in 19 (54.3%) patients and postoperative complications include joint stiffness 2(5.7%), painand stiffness 3(8.6%), bony ankylosis2(5.7%) and limb shortening 1(2.9%).

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