alexa Solitary Fibrous Tumors(SFT) | Argentina | PDF | PPT| Case Reports | Symptoms | Treatment

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Solitary Fibrous Tumors(SFT)

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  • Solitary Fibrous Tumors(SFT)

    Disease Definition: Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura or at virtually any site in the soft tissue including seminal vesicle. Approximately 78% to 88% of SFT's are benign and 12% to 22% are malignant. It is a heterogeneous group of rare spindle-cell tumors that include benign and malignant neoplasms. Their cell of origin is still debated. SFT is preferred by most pathologists as a better term than “hemangiopericytoma” that gathers numerous unrelated entities and is presently only employed by neuropathologists. We focus the present paper on the forms of this family of tumors occurring in adult patients. There are 3 typical primary locations: pleural, meningeal and extrathoracic soft tissue. 

  • Solitary Fibrous Tumors(SFT)

    Disease Symptoms: Patients present with proptosis and possibly ptosis, eyelid swelling, tearing, diplopia or decreased vision. Malignant infiltrating lesions can sometimes cause pain.
    Disease Treatment: Because even benign-appearing solitary fibrous tumors (SFTs) can be locally recurrent and metastatic, wide resection of both benign and malignant SFTs is recommended. Preoperative vascular studies and arterial embolization should be considered because of the known bleeding risk with resection. Careful exclusion of other diagnoses (eg, synovial sarcoma) is important. Because of the favorable outcome with SFTs, it may be possible to avoid limb-threatening and deforming operations. No evidence suggests that adjuvant chemotherapy is beneficial. If the SFTR appears malignant histologically, adjuvant radiation therapy may be considered. Long-term follow-up is recommended because local and distant relapse is possible, even with benign-appearing tumors. 

  • Solitary Fibrous Tumors(SFT)

    Statistics: In argentina country, the Six patients were included; 83.3% were females. Mean age was 48 years. All patients were symptomatic, mainly dyspnea, cough and chest pain; 66.7% were left-sided. Preoperative angiography and embolization were per formed in 83.3% cases with successful surgical resection. The predominant blood supply was derived from the internal mammalian artery. Intraoperative complication rate was 17%. A vascular pedicle was found in 66.7%. The largest lesion was 40 cm in diameter and weighed 4500 g. Only one case showed high mitotic activity. Mean follow-up to date is 14 months. Symptomatology found was consistent with previous reports but in higher percentages. Accurate diagnosis is critical because surgical resection involves a potential cure; however, long-term follow-up is mandatory. Preoperative embolization is recommended due to tumor size.

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