S.No. Ingredients F1(mg) F2(mg) F3(mg)
1. Nizatidine 75 75 75
2. HPMC K4M(D:P) 75
(1:1)
112.5
(1:1.5)
150
(1:2)
3. NaHCO3 (10%) 35 35 35
4. Aerosil (1%) 3.5 3.5 3.5
5. Magnesium stearate (1%) 3.5 3.5 3.5
6. Lactose 158 120.5 83
Total Weight- 350 mg
Table 1: Composition of nizatidine floating tablets prepared with HPMC K4M.