Time CF1 CF2 CF3 CF4 CF5 CF6 CF7 CF8 CF9
0 0 0 0 0 0 0 0 0 0
60 13.50 6.00 3.00 2.40 1.8 0.00 0.00 0.00 0.00
120 25.28 12.03 7.52 6.61 5.71 4.80 2.70 0.30 0.30
180 32.32 19.90 16.56 14.75 10.54 9.33 6.32 3.60 3.61±
240 37.29 23.91 23.55 25.93 16.00 12.68 11.45 10.52 4.83
300 45.3 31.54 29.68 35.08 24.79 17.25 13.91 20.48 20.45
360 49.45 43.12 41.84 41.27 30.93 22.74 20.59 30.79 28.37
420 59.45 52.57 49.81 51.31 38.91 30.46 28.32 40.89 40.86
480 68.94 63.79 58.85 59.48 46.61 37.44 41.26 55.19 53.05
540 81.62 74.89 66.37 65.80 52.27 42.74 54.69 65.39 69.54
600 87.46 84.90 74.23 75.76 69.65 49.88 72.69 78.95 84.02
660 97.54 94.06 86.94 84.87 75.13 62.45 87.19 92.28 98.27
Table 8: Results of in vitro dissolution studies of Nizatidine floating osmotic tablets-spray coating (CF1-CF9).