Figure 7: Summary of the unique aromatic-aromatic interactions observed in the crystals of peptides I-III. The parameters Rcen, ç, and Rclo are indicated: (a-c) peptide I; (d-k) peptide II; (l-o) peptide III. Figure 8 clearly shows van der waalsinteractions and molecular conformation of the peptides in crystal the benzyl group-the side chain molecular structure packing is attached with hydrogen. All the crystal was grown in water /methanol equimolar combination[19-21].