Phenotype 
Number of GxE data points 
Environmental factor 
Number of GxE data points 
obesity phenotypes 
98 
physical activity 
109 
BMI 
40 
fat, total, percent energy from 
57 
waist circumference 
17 
SFA, percent energy from 
46 
delta body weight 
12 
PUFA, percent energy from 
33 
delta fat mass 
6 
highfat challenge 
29 
lipid phenotypes 

MUFA, percent energy from 
24 
HDLC 
85 
alcohol 
20 
triglyceride 
44 
Mediterranean diet 
15 
cholesterol, total 
33 
lowenergy diet 
12 
LDLC 
29 
lowfat diet 
12 
delta LDLC 
9 
PUFA, N3, percent energy from 
12 
APOA1, plasma 
8 
fish oil 
11 
APOB, plasma 
7 
diet, in general 
10 
APOC3, plasma 
7 
smoking 
10 
delta cholesterol, total 
7 
dietary cholesterol 
9 
delta HDLC 
7 
PUFA, N6, percent energy from 
9 
triglyceride:HDLC ratio 
7 
SFA:CHO ratio 
9 
LDLC:HDLC ratio 
5 
NCEP1 diet 
7 
insulin phenotypes 

fenofibrate 
6 
insulin resistance (HOMAIR) 
17 
PUFA:SFA ratio 
5 
glucose, 2h 
8 


type 2 diabetes 
8 


glucose, fasting 
6 


insulin, fasting 
6 


vascular phenotypes 



blood pressure, systolic 
9 


intimamedia thickness 
9 


homocysteine, plasma 
5 


Creactive protein, plasma 
4 


