Gene set PPARA network PPARG network AIDM Olive oil response
n 224 252 422 103
shared genes ACSL1, ACSL5, ANGPTL4, APOA1, APOA2, APOA5, APOC3, CD36, CPT1A, CPT1B, CYP3A5, FABP2, FADS1, IL1B, IL6, IL6R, LEPR, LIPC, LIPE, LIPG, LPL, MTTP, NFKB1, NR1H3, PLIN1, TNF, UCP2, UCP3 ACSL1, CD36, EDNRA, FHL1, LIPE, LPL, NR1H3, PLIN1, PPARG, UCP2 ADIPOQ, APOA1, APOC3, CETP, F7 CDKN2A, IL1B, IL6
fold enrichment 26.7 10.0 3.0 7.4
highly represented phenotypes HDL-C, triglyceride HDL-C, HOMA-IR, BMI HDL-C, LDL-C, total cholesterol ND
highly represented environmental factors dietary fat, high-fat challenge, PUFA, SFA physical activity, dietary fat, SFA, fish oil MUFA ND
n = number of genes in the respective gene set
Table 6: Comparison of four nutrigenomics gene sets to the GxE database.