Figure 2: The site-by-site variation analysis of A1pp domains among AT1G69340, AT2G40600 and YMX7_YEAST. We extracted the conserved domain of AT1G69340, AT2G40600 and YMX7_YEAST by SMART. We took the alignment of the three proteins, and then gained the site-by-site statistic of the conserved domain using weblogo 3.3 ( Error bars indicated an approximate 95% Bayesian confidence interval. The information content of a site (bits) is defined as the relative entropy of the monomers at the site to the background distribution.