Figure 2A: The last five exons of LMNA gene showing G>T substitution in codon 527 (exon 9), at base position 1580 of LMNA gene coding region (c.1580G>T), causing substitution of (CGT) for Arginine to (CTT) for Leucine, at position 527 of Lamin A/C protein (p.Arg527Leu).