| |
IFN-γmethylation status |
SOCS1 methylation status |
| Variables |
U (n=7) |
U/M (n=59) |
M (n=30) |
P |
U (n=89) |
U/M (n=5) |
M (n=2) |
P |
| Age (Years) |
40
(30-61) |
48
(30-70) |
50.5
(30-70) |
0.49a |
50
(30-70) |
44
(30-65) |
47.5
(35-60) |
0.957a |
| Sex (M/F), n% |
3/4
(42.9/5.1%) |
35/24
(59.3/40.7%) |
19/11
(63.3/36.7%) |
0.61b |
54/35
(60.7/39.3%) |
3/2
(60/40%) |
0/2
(0/100%) |
0.225b |
| Creatinine (mg/dl) |
9.1
(5.2-11.6) |
8.57
(5-14.5) |
6.3
4.2-14.33)) |
0.012a* |
7.66
(4.2-14.5) |
9
(5.2-11) |
9.3
(7-11.6) |
0.733a |
eGFR
(ml/min/1.73 m2) |
6.36
(3.96-9.79) |
6.68
(2.86-13.91) |
8.12
(3.46-14.09) |
0.018a* |
7.03
( 2.86-14.09) |
7.29
(5.04-9.74) |
5.16
(3.96-3.36) |
0.366a |
| Hemodialysis Duration (Months) |
24
(12-48) |
36
(7-108) |
24
(7-108) |
0.62a |
36
(7-108) |
24
(12-36) |
30
(24-36) |
0.431a |
| Urea (mg/dl) |
105
(62-144.32) |
104.54
(54.5-186.9) |
109.76
(51.1-184.5) |
0.89a |
105
(51.1-186.9) |
95.45
(89.7-120.4) |
99.77
(79.5-120) |
0.947a |
| Total Cholesterol(mg/dl) |
225.80
(122.5-264.5) |
161.29
(103.2-332) |
148.4
(103.23-310) |
0.041a* |
154.83
(103.23-332) |
220
(141.9-258.06) |
174.19
(122.6-225.8) |
0.165a |
| Triglyceride(mg/dl) |
166.66
(136.6-266.7) |
166.66
(91.1-366.7) |
145.32
(106.2-244.4) |
0.20a |
151.76
(91.1-327.8) |
177.14
(151.7-366.67) |
201.62
(136.6-266.7) |
0.268a |
| HDL-C (mg/dl) |
35.29
(30.88-39) |
32.81
(20.59-60.2) |
30.88
(21.88-47.06) |
0.28a |
32.35
(20.59-60.2) |
32.35
(31-39.71) |
35.14
(35-35.29) |
0.790a |
| VLDL-C (mg/dl) |
33.33
(27.32-53.33) |
33.33
(18.21-73.3) |
29.06
(21.25-48.9) |
0.204a |
30.35
(18.2-65.56) |
35.42
(30.35-73.3) |
40.32
(27.32-53.33) |
0.268a |
| LDL-C (mg/dl) |
149.11
(60.26-200.3) |
92.13
(21.3-255.1) |
80.58
(41.8-236.3) |
0.103a |
83.48
(21.3-255.1) |
152.37
(74.8-190.56) |
98.72
(60.3-137.2) |
0.237a |
| Systolic BP(mm Hg) |
180
(120-180) |
150
(110-185) |
140
(110-190) |
0.26a |
150
(110-190) |
130
(120-180) |
150
(120-180) |
0.644a |
Diastolic BP
(mm Hg) |
95
(70-100) |
90
(65-100) |
90
(70-100) |
0.14a |
90
(65-100) |
80
(70-100) |
92.5
(85-100) |
0.453a |
Data are presented as median (range).
U Total unmethylation (only the unmethylated allele)
U/M Partial methylation (both unmethylated and methylated alleles)
M Total methylation (only the methylated allele)
aKruskal-Wallis test.
bChi-square test.
*Statistically significant compared at P<0.05.
eGFR estimated glomerular filtration rate. |
