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Figure 3: Schematic presentation of the experimental model regarding the immunological effects of asbestos on NK cells. When NK cells were exposed to chrysotile (white asbestos), the expression of activation receptors changed as evidenced by the reduced expression of NKp46. These findings were also found in patients with pleural plaque ormesothelioma. The surface expression of NKp46 is a candidate for use as a bio and predictive marker of asbestos exposure and the occurrence of mesothelioma. |