| Hematological parameters |
Groups |
| Control |
100 mg/kg |
200 mg/kg |
400 mg/kg |
| RBC (×106/uL) |
8.48 ± 0.28 |
7.71 ± 0.20 |
7.87 ± 0.33 |
8.12 ± 0.40 |
| HBG (g/dL) |
17.00 ± 0.62 |
16.00 ± 0.44 |
15.83 ± 0.15 |
16.30 ± 0.57 |
| HCT (%) |
46.53 ± 2.65 |
43.00 ± 0.62 |
43.16 ± 0.64 |
44.17 ± 1.83 |
| MCV (fL) |
54.87 ± 1.30 |
55.90 ± 1.64 |
54.96 ± 2.23 |
54.55 ± 1.09 |
| MCH (pg) |
15.71 ± 1.28 |
16.05 ± 0.75 |
14.98 ± 1.02 |
15.37 ± 1.35 |
| MCHC (g/dL) |
36.53 ± 1.75 |
37.20 ± 0.37 |
36.60 ± 0.65 |
36.77 ± 0.69 |
| RDW (%) |
14.56 ± 0.57 |
14.60 ± 1.02 |
13.20 ± 1.80 |
14.10 ± 1.62 |
| WBC (×103/uL) |
8.66 ± 1.51 |
10.90 ± 0.00 |
17.30 ± 10.39 |
13.27 ± 1.17 |
| Lymphocytes (%) |
75.66 ± 10.02 |
77.00 ± 0.00 |
74.33 ± 2.51 |
75.25 ± 7.13 |
| Neutrophils (%) |
23.00 ± 9.53 |
22.00 ± 0.00 |
23.00 ± 1.00 |
22.00 ± 6.98 |
| Monocytes (%) |
0.66 ± 1.15 |
1.00 ± 0.00 |
0.66 ± 1.15 |
2.00 ± 0.81 |
| Eosinophils (%) |
0.66 ± 0.57 |
0 ± 0 |
0 ± 0 |
0.75 ± 0.50 |
| PLT (×103/uL) |
1024.66 ± 147.65 |
1139.00 ± 67.45 |
1045.33 ± 52.20 |
1083.00 ± 38.74 |
| Data are expressed as mean ± S.D. One way ANOVA followed by Tukey test, when appropriate. Red Blood Cells counts (RBC), Hemoglobin (HGB), Hematocrit (HCT), Mean Corpuscular Volume (MCV), Mean Cell Hemoglobin (MCH), Mean Cell Corpuscular Hemoglobin Concentration (MCHC), Red cells Distribution Width (RDW), Leukocytes (WBC) and Platelet (PLT). Differences between groups were considered to be significant when p < 0.05. |
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