| Antibiotic Class |
Representative Compounds |
Target-mode of action |
| b-Lactams |
Penicillin
Cephalosporin
Monobactams
carbapenems |
Penicillin-binding proteins (PBPs)-inhibition of transpeptidation |
| Ribosomally made peptides |
Lantibiotics (ex nisin)
Defensins (ex plectasin) |
Lipid II-pore formation
Lipid II |
| Glycopeptides |
Vancomycin
Teicoplanin
Telavancin
Dalbavancin
Oritavancin |
Lipid II-(D-Ala-D-Ala) |
| Cyclic lipo(depsi-)peptides |
Ramoplanin
Katanosin B
Bacitracin |
Lipid II
C55-PP |
| Amino acid analogs |
D-cycloserine
Fosfomycin |
DdlA
MurA |
| Sugar substrate analogs |
Tunicamycin
moenomycin |
MraY
PBPs-inhibition
of transglycosylation |
